When you are particularly irritable, you need to actively self-adjust, or you can consider taking medication. In terms of self-adjustment, you must do what you should do, learn to focus on the present moment and do what you should do, not to be in pain, sadness and irritability. And you must do what you are interested in, use your energy on things that interest you and are more valuable, only then can you achieve happiness and joy. Medication Currently, if the irritability is relatively mild, you can take vitamins for treatment, such as vitamin B1 or glutamine. You can also take Chinese medicine for treatment and adjustment, such as Jiu Wei Zhen Xin Granules and An Xin Nian Nang Bei Liquid, etc. These drugs belong to Chinese medicine extracts, which are relatively mild, have relatively few side effects, and have relatively high patient resistance, so they can be used with confidence. When severe irritability appears, or even has appeared for 2 months and more, seriously endangering their daily life, you can consider benzodiazepine anti-anxiety drugs, such as taking lorazepam, oxazepam, alprazolam, diazepam, etc. Some of these drugs can not be taken in large quantities for a long time, because there is a certain dependence.