If it is simply an irritable mood without symptoms such as panic, chest tightness and shortness of breath, one should review whether there are any recent mental-emotional effects such as excessive work stress, poor sleep quality, late nights and interpersonal tension. If it is a woman it should be combined with the possibility of being in perimenopause, due to hormonal disorders leading to menopausal syndrome. If the irritability is accompanied by irritability, hand trembling, neck mass, panic and other symptoms and signs, thyroid function should be checked to exclude the possibility of hyperthyroidism. In Chinese medicine, irritability is caused by excessive fire in the heart, deficiency of heart yin, unrestrained liver qi, liver stagnation and fire, etc. The possibility of diseases should be investigated according to the presence of accompanying symptoms and positive signs. After ruling out diseases, mental and emotional causes should be self-regulation, sleep improvement, psychological counseling if necessary, and Chinese medicine can also have a better treatment effect.