Alpha-fetoprotein 45 indicates that the patient may suffer from hepatitis, cirrhosis, primary liver cancer, malignant tumors of embryonic origin, etc., and should improve the abdominal ultrasound, CT, MRI and other examinations in time to clarify the cause of the disease and give timely treatment. Alpha-fetoprotein is a commonly used clinical tumor marker, its normal value range is less than 20, 45 is an indicator of elevation, generally suffering from some clinical non-tumor diseases or tumor diseases, easy to cause abnormal elevation of this indicator. Non-tumor diseases include acute active stage of viral hepatitis B or post-hepatitis cirrhosis. Tumor diseases include primary hepatocellular carcinoma and malignant tumors of embryonic origin, such as choriocarcinoma. It is suggested that other examinations should be perfected to clarify the etiology.