Systemic inflammatory response syndrome (SIRS): It is a systemic inflammatory response of uncontrolled self-sustained amplification and self-destruction of the organism caused by the action of infectious or non-infectious etiologies on the organism. It is a clinical process in which the organism experiences an excessive stress response for repair and survival. When the body is hit by exogenous damage or infectious toxic substances, the initial inflammatory response can be triggered, while the body produces endogenous immune inflammatory factors to form a “waterfall effect”. SIRS is most likely to be triggered in critically ill patients due to reduced compensatory anti-inflammatory response and metabolic dysfunction, which can lead to multiple organ dysfunction syndrome (MODS) in severe cases. So, what tests are needed for patients with peripheral inflammatory reactions? The following is a brief introduction: 1. Fly maggot examination, fly maggot examination is a dermatological test to check the presence of fly maggots that cause skin disease. Fly maggot disease is a parasitic disease caused by the larvae (maggots) of flies that live in the organs or tissues of people or animals. Cutaneous fly maggot disease is an inflammatory reaction caused by the larvae of certain flies burrowing into the skin. 2.Neutrophil count (NEUT), neutrophils are an important part of the body’s defense system and are associated with the body’s non-specific anti-infection process. These cells have a powerful phagocytic bactericidal function, and their course of action is through chemotaxis, recognition and binding of phagocytic substances, and then intracellular uptake, ultimately killing and degrading pathogens. 3, free protein S assay, free S protein assay is to diagnose the disease by measuring the content of free S protein in human body. Free S protein is an alpha single-chain glycoprotein in serum with a molecular weight of 83 kDa. The main regulatory role of SP is to compete with the sub-stable binding site of C5b~7 for target cell membrane lipids and to deprive C5b~7 of its membrane binding activity by forming a hydrophilic SPC5b~7 (abbreviated as S5b~7) complex. In this way, cells adjacent to the complement activation site are protected from incidental attack.