The pharmacological treatment of ischemic cerebrovascular disease involves early thrombolytic therapy to restore blood oxygen supply. To improve cerebral circulation, reduce cerebral metabolism, and reduce cerebral edema. Systemic therapeutic drugs to correct hyperglycemia, reduce blood viscosity, and maintain water-electrolyte balance. To prevent the recurrence of cerebral embolism, stabilize the patient’s condition, organize the further development of cerebral infarction, reduce neurological deficits as much as possible, and prevent complications. I. Treatment mechanism: thrombolysis, antisepsis, fibrin-lowering II. Selection of therapeutic drugs 1. Thrombolysis is used in the ultra-early stage (within 6h of onset), (1) commonly used drugs include alteplase, (2) must be used within 3h of onset (3) Precautions: Gastric mucosal protective agents should be given at the same time as thrombolysis; low-molecular dextrose or 20% mannitol injection can be given intravenously before thrombolysis; monitor blood pressure before, during and after treatment (2) anticoagulation therapy, commonly used heparin, indications for heparin anticoagulation therapy: transient ischemic attack, cerebral thrombosis and cerebral embolism, especially transient ischemic attack is the most effective (3) anti-platelet aggregation drugs. (4) vasodilators commonly used drugs include ginkgo biloba preparations, which have good therapeutic effect on ischemic cerebrovascular disease (5) dehydration drugs 20% mannitol injection can reduce cerebral edema to reduce the infarct area and prevent disability (6) commonly used calcium channel blockers include nimodipine, nicardipine, verapamil (7) Use of cerebral metabolic activators such as cytarabine cathepsin.com 3. Recovery period: Oral vitamins E and C, antioxidants such as ginkgo biloba preparations, herbal preparations to activate blood circulation and remove blood stasis, and low-dose aspirin can be used to achieve the purpose of recovery treatment. Pharmacological treatment of hemorrhagic cerebrovascular disease The main treatment principle in the acute phase is to prevent further bleeding and reduce intracranial pressure. It is important to keep quiet and minimize unnecessary moving. It is important to keep the airway unobstructed to prevent severe cerebral hypoxia. If sputum secretion is high, tracheotomy should be made early cataract education network collection. Drug therapy I. Treatment mechanism: Mannitol reduces intracranial pressure through osmotic dehydration and is a free radical scavenger; nimodipine improves cerebral blood flow and reduces calcium overload; N-acetyl heparin inhibits complement activation and reduces cerebral edema. Second, the choice of therapeutic drugs 1, control cerebral edema, reduce intracranial pressure: mannitol injection and compound glycerol injection at the same time or alternately, compound glycerol injection or glycerol fructose injection 500ml static push; sodium heptaerythroside 2, moderate lowering of blood pressure to prevent further hemorrhage: intramuscular injection of lisperdalin, static sodium nitroprusside or nifedipine 3, the application of hemostatic drugs: hemostatic agents cataract education network collection 4. Artificial hibernation head cooling therapy: the use of No. 1 hibernation combination 5, stress upper gastrointestinal bleeding treatment: omeprazole, cimetidine, also can be injected from the gastric tube thrombin 6, the use of anti-epileptic drugs: phenytoin sodium, try not to use diazepam class and barbiturates