Massive cerebral infarction is an extremely serious form of ischemic stroke. These diseases have high mortality and disability rates, and according to statistics, about 70% of patients with massive cerebral infarction survive for about one week, especially elderly patients with underlying disease. Only less than 30% of patients can survive longer with early aggressive treatment such as dehydration to lower cranial pressure and decompression of the debridement flap, with an average survival time of about 3 years. Most of these patients will be left with severe neurological deficits, and patients are often bedridden and will eventually die from serious complications such as pneumonia, malnutrition, urinary tract infections, decubitus ulcers, and deep vein thrombosis. Massive cerebral infarction is usually caused by occlusion of large blood vessels due to cardiogenic stroke, and patients can present with severe and persistent symptoms of neurological deficits, such as coma, hemiparesis, gaze, seizures, etc. It is extremely important for early recognition of cardiac disease to significantly reduce the incidence of massive cerebral infarction as well as to improve the prognosis.