Coleraine syndrome, which should be Klein-Levin syndrome, is a rare neurological disorder characterized by recurrent excessive sleepiness and behavioral changes. The main clinical manifestations are somnolence and abnormal sleep, and sudden collapse. 1. Somnolence and abnormal sleep: during the onset of the disease, patients can be asleep at any time and place, and no stimulus can wake them up, but patients can wake up on their own to eat and defecate, and often sleep for more than ten hours or even more than twenty hours at a time. In sleep or wakefulness, some patients may not be able to move, unable to speak, or even unable to take a deep breath of sleep paralysis phenomenon, some patients will also appear before sleep hallucinations such as hallucinations, hallucinations and other hallucinations before going to sleep. 2. Sudden collapse: patients may suddenly experience reversible hypotonia or loss of muscle tone, with forward head tilt, arm drop, knee abduction, and anterior tilt of the spine. The frequency of seizures varies from person to person. When the muscle tone is completely lost, the patient will often fall heavily to the ground, which may cause serious consequences such as skull fracture. Family members should usually do a good job of protecting the patient’s safety, and if the phenomenon of repeated sudden falls and other phenomena, it is recommended to go to the hospital in time to seek medical help.