Neurological paralysis is mainly caused by brain, spinal cord and peripheral nerve injury or lesion. Paralysis caused by brain and spinal cord lesion or injury is central paralysis, such as hemiplegia, quadriplegia, paraplegia, etc.; paralysis caused by peripheral nerve injury or lesion is peripheral paralysis, such as peripheral facial paralysis, radiculitis, nerve injury such as brachial plexus nerve injury, radial nerve injury, etc. Neurological paralysis involves several related disciplines such as neurology, orthopedics, otorhinolaryngology, rehabilitation medicine, and physical therapy. This poses a dilemma for patients to choose the most effective treatment method to give them the best results. It also places a higher demand on the rehabilitation doctor to diagnose the type and degree of neurological paralysis and provide the most suitable treatment to the patient. Patient selection: according to the damage or lesion, such as nerve cutting injury, first choose the orthopedic surgical anastomosis method of treatment, then rehabilitation; brain hemorrhage, cerebral infarction in the acute stage first choose neurology, and early rehabilitation after the condition is stabilized. Patients with neurological paralysis should be treated with early rehabilitation after their condition is stabilized. In addition to the knowledge of neurological rehabilitation, rehabilitation doctors should be proficient in neuroanatomy, neurology and orthopedics and other related knowledge, and cultivate a meticulous working style. In clinical work, careful clinical examination is very important to discover subtle changes after nerve damage, and through this change, determine the degree of nerve damage or lesion. With the rapid development and clinical application of large testing equipment, it has been found from our clinical practice for many years that the false positives of these test results are very high. Therefore, careful clinical examination is more helpful to determine the degree of nerve damage and prognosis, and it also requires doctors to have good knowledge related to neuroanatomy, neurology and orthopedics, and the accumulation of these knowledge and experience needs to be cultivated through hard work.