Monoplegia, also referred to as monoplegia, is rare among the many types of cerebral palsy. Moreover, this monoplegic cerebral palsy disease is formed due to the phenomenon of a limited focal area in one part of the cortex. Although this monoplegia is not the most serious, it is not as easy to improve in treatment methods as other common types because this type is relatively rare. The causes of monoplegia are as follows: monoplegia is a paralysis of one of the four limbs. Monoplegia can be caused by peripheral neuropathy and central neuropathy. Lesions can be located in the anterior horn of the spinal cord, anterior roots, plexus and peripheral nerves. Acute onset is seen with trauma, while gradual take-off is seen with compression of the plexus and nerve roots, such as tumors and cervical rib compression. Monoplegia is due to peripheral neuropathy and is characterized by lower motor neuron paresis, i.e., flaccid paralysis. Muscle atrophy is evident, tendon reflexes are reduced or absent, and there are signs and symptoms such as sensory disturbances, pain, vasomotor disorders, and nutritional disturbances. Anterior root or anterior horn cell lesions palsy is segmental. Lesions of the anterior horn alone have no sensory disturbance, and in acute cases, acute gray matter, and in chronic cases, progressive spinal muscular atrophy, with more pronounced muscle atrophy than paresis, and muscle bundle tremor. Similar chronic paresis can occur with spinal cord cavitation and anterior horn, but there is sensory dissociation with segmental loss of pain and temperature sensation and presence of touch. Anterior root damage is often associated with radicular pain and segmental sensory deficits due to simultaneous damage to the posterior roots. Common causes of nerve root lesions are tumors of the spinal membrane and spine, inflammation, tuberculosis, trauma, and disc herniation. In the case of peripheral nerve lesions, it is paralysis of the muscles or muscle groups innervated by that nerve and hyperalgesia or loss of sensation in their distribution, loss of corresponding tendon reflexes, and often atrophy in the case of severe long-term damage. So it is said that monoplegia is mostly caused by local trauma, fracture, deconditioning, compression, ischemia, etc.