What is called braking syndrome, what are the clinical manifestations: due to disease, trauma caused by the loss of motor function, or due to prolonged bed rest and braking and cause a series of pathophysiological reactions, in the clinical manifestation of the syndrome is called braking syndrome. Its clinical manifestations are as follows: 1, musculoskeletal system: wasting atrophy, muscle weakness, anterior segment contracture, osteoporosis. 2, cardiovascular system: erectile dyskinesia, muscle weakness, contracture of the anterior segment, osteoporosis. Cardiovascular system: upright hypotension, cardiovascular hypoplasia, decreased plasma volume, and thromboembolism. 3.Nervous system: abnormal sensation, decreased pain valve, low mood, inhibition, anxiety, decreased orientation. 4.Respiratory system: tidal volume and ventilation per minute are reduced, cough and tracheal cilia activity are reduced, transverse septal activity is weakened, and episodic pneumonia is present. 5, digestive system: loss of appetite, constipation. 6.Urinary system: urinary tract infection, urinary tract stone formation. 7.Endocrine system: deterioration of glucose tolerance, increase of parathyroid hormone in serum, decrease of androgens and spermatogenesis. 8, metabolism: negative nitrogen balance, negative sulfur and phosphorus balance. 9, skin: skin atrophy, bedsores.