Fasting urine osmolality of 573mOsm is not normal, normal human urine osmolality should be greater than >600mOsm/kg-H2O, osmolality reduction can be seen in chronic pyelonephritis, chronic renal failure, uremic syndrome.
1.Chronic pyelonephritis: mostly caused by gram-negative bacillus infection, with urinary frequency, urgency, painful urination as the main manifestation. When the urine concentration ability decreases, polyuria and nocturia may appear.
2. Chronic renal failure: it is the decline of renal function caused by various reasons, and fibrosis of kidneys, etc. It is mainly manifested by anorexia, nausea, vomiting, anemia, hypertension and other symptoms.
3. Uremia: the lack of antidiuretic hormone leads to a decrease in the reabsorption of water by the kidneys, and its main clinical features are polyuria, irritable thirst, hypotonic urine and so on.
Patients with abnormal urine osmolality should go to the hospital for examination to clarify the cause of the disease, and be treated under the guidance of a professional physician to avoid delaying the condition.