EBV is a herpes virus that can produce some elevated antibodies after infection. For most adults with a previous infection, there will only be two elevated antibodies: IgG antibodies to the EBV nuclear antigen and IgG antibodies to the EBV capsid antigen. If only these two antibodies are elevated, this indicates a previous infection and is not indicative of a primary infection or a recurrent infection, so there is no need to treat this condition. If there is an elevation of IgG or IgM to the early EBV antigen or an elevation of IgM to the EBV capsid antigen, this is usually a primary infection or an active virus. If this is accompanied by significant fever, lymph node enlargement or mononucleosis, the patient should be treated accordingly and the appropriate antiviral medication can be applied.