Both mycoplasma and chlamydia are pathogenic microorganisms that are intermediate between viruses and bacteria. Mycoplasma and chlamydia infections are prone to respiratory symptoms and can also infect the eye and genitourinary system, which may present with symptoms such as sore throat, dry cough, conjunctival congestion, urinary urgency, and painful urination. Clinical symptoms vary depending on the site of infection and the infecting mycoplasma and chlamydia. 1. Respiratory symptoms: If the infection is caused by Mycoplasma pneumoniae or Chlamydia psittaci, it usually invades the respiratory tract and can cause infection of the upper or lower respiratory tract, and patients usually show symptoms of fever with sore throat and irritating dry cough; 2. Eye symptoms: If the infection is caused by Chlamydia trachomatis eye infection, can lead to trachoma, manifested as conjunctival congestion, tearing, lid conjunctiva visible follicles, may be accompanied by purulent discharge, usually patients will have a foreign body sensation in the eyes; 3, genitourinary system symptoms: if the genitourinary tract of mycoplasma, chlamydia infection, such as mycoplasma solium, human mycoplasma and mycoplasma trachomatis caused by infection, due to different sites of infection, gender, patients can appear different clinical manifestations The clinical manifestations may vary depending on the site of infection and gender . If the infection is confined to the urinary system, patients can experience frequent urination, urgency, painful urination, difficulty in urination or a feeling of incomplete urination, and there will be purulent urethral discharge and redness and swelling of the urethral orifice. In addition, male patients can also cause orchitis, which manifests as pain in the testicles and swelling of the scrotum. Female patients can cause vaginitis, cervicitis, and ureteritis. If it causes cervical or vaginal inflammation, there will be increased leucorrhea and odor. If it causes pelvic inflammatory disease, there can be hidden pain and pressure pain in the lower abdomen or adnexal area; 4. Other symptoms: For chlamydia infection, some patients can also show local inguinal lymph node enlargement. If the disease is prolonged it can cause local lymph node rupture, ulceration and formation of fistula.