There are several possible causes of swollen feet in pancreatic cancer patients: I. Hypoproteinemia, pancreatic cancer patients are often unable to eat due to tumor obstruction of the digestive tract, consumption of the tumor itself, or lack of appetite do not want to eat, the nutritional situation is extremely poor, the concentration of albumin in the blood drops significantly, resulting in extremely low blood colloid osmotic pressure, water leakage from the blood to the tissue interstices and causing edema, the drooping parts of the body, such as The foot is more obvious. At the advanced stage of pancreatic cancer, the mass will compress the adjacent blood vessels or lymphatic vessels, and the enlarged lymph nodes caused by lymph node metastasis will also compress the blood vessels, which will lead to obstruction of venous or lymphatic flow in the lower limbs and increase the pressure in the blood vessels or lymphatic vessels, resulting in edema due to water leakage out of the tissue interstices. Patients with advanced malignant tumor have different degrees of anemia, and severe anemia can lead to obvious edema.