Pediatric intussusception, commonly known as “intestinal tangles”, is an obstruction of the intestine caused by a segment of the intestine and its corresponding mesentery being trapped in the lumen of the adjacent intestine. It is a unique disease in infancy. It is common in infants and children within 2 years of age, especially in infants aged 4-10 months, and the incidence decreases with age. Spring is the most common season for pediatric intussusception. Due to the different parts of the intussusception, intussusception can be divided into ileocecal, ileocolic, ileo-ileocolic, small intestine, colonic and multiple types, among which the ileocecal type is the most common, accounting for 50-60% of the total. If your baby has paroxysmal crying, vomiting, solving jam-like stools and abdominal masses, be alert to the presence of “intestinal knots”. After the occurrence of intussusception, whenever a wave of intestinal peristalsis pushes the intestinal tube forward, the mesentery is pulled, the sheath of intussusception will have strong contractions and severe pain, the child will suddenly appear crying and restless, and form paroxysmal attacks. The vomiting is reflexive at first, and the vomit is mainly stomach contents such as milk and milk lumps, later vomiting may be yellow-green bile, and 1-2 days later the vomit may be foul-smelling intestinal contents, when the obstruction of the intestine is very serious. In 70-80% of children, a lump shaped like a salami can be palpated in the abdomen. Therefore, once your baby shows the above four symptoms, you should be highly alert to whether your baby’s intestines are knotted and should go to the hospital immediately. Air enemas and minimally invasive laparoscopic treatment save babies with knotted intestines from the pain of surgery. Once a baby is suspected of intestinal entrapment, air enema can be performed first. Through air enema, the diagnosis of intestinal entrapment can be clarified, and at the same time, the entrapped intestine can be reset to achieve the purpose of treatment. In hospitals with strong technical strength in pediatric surgery, the success rate of air enema repositioning is up to 90% or more. However, air enema also has the risk of intestinal perforation, and there are many children who have failed air enema or repeatedly re-infarcted after repositioning because of the long time of intestinal entrapment (more than 48 hours), the presence of intestinal organic lesions (such as small intestinal polyps, small intestinal diverticula, etc.) and the rare ileocolic intestinal entrapment. For these cases, open surgery, i.e., cesarean section, was required in the past. Since the introduction of minimally invasive laparoscopic surgery for pediatric intussusception, this situation has fundamentally changed. The baby’s abdominal cavity can be clearly observed on a TV screen by simply placing two small holes in the abdominal wall and inserting a laparoscope. Performing an air enema under television laparoscopic surveillance significantly suggests the success of its repositioning and minimizes the incidence of bowel perforation. If other lesions such as polyps and diverticula are found, they can be treated promptly under laparoscopy, sparing the child the pain of open surgery. Therefore, it is safe to say that babies with “knotted intestines” can be treated without surgery.