Due to the abolition of the mandatory pre-marital medical examination system, the important aspect of a thorough understanding of health conditions before marriage is increasingly forgotten. As a matter of fact, certain medical check-ups before marriage are still necessary. Among them, the exclusion and screening of anal and intestinal diseases are still very necessary for lesbians who are preparing to be mothers-to-be. In our expert clinic, we found a lot of pregnant women, pregnancy complications of various anorectal diseases, treatment dare not use too much medicine, no treatment and pain and suffering, doctors, patients are very passive. Premarital at least should pay attention to the following points: (1) do a physical examination of the anus, to exclude anorectal diseases. (2) if usually have hemorrhoids, not too serious, should pay attention to local hygiene, avoid spicy stimulating food, to prevent hemorrhoids further increase; if the hemorrhoids have been more serious, should be surgical resection first. (3) If you usually have anal fissure symptoms, such as anal fissure pain, you should first use drugs or adjust the diet, first to keep the bowel movement; and then external use of some drugs, and strive for anal fissure self-healing. If the symptoms of anal fissure are serious, or the attacks are frequent, surgery should be done first; (4) Patients with habitual constipation should develop a good habit of regular defecation through medication, diet, habit cultivation and other ways, so as to prevent constipation after pregnancy, which is difficult to deal with. (5) Other anorectal diseases should also be properly treated under the guidance of the doctor. As the abdominal pressure increases significantly during pregnancy, the abdominal cavity and perianal venous system blood reflux is significantly affected, anal and intestinal diseases have become one of the common diseases during pregnancy, hemorrhoids, anal fissure pain, constipation and discomfort will bring pain during pregnancy, so please prepare to become a mother of lesbians to pay attention to.