Congenital colonic stenosis is clinically rare, and most of them develop in the neonatal period and are treated. Recently, a case of sigmoid colon stenosis in a 5-month-old patient was successfully treated in our department, which is reported as follows. Patient, male, 5 months. He was admitted to the hospital on May 7, 2008 because of recurrent and intermittent episodes of abdominal distension and diarrhea for 4 months, and worsening abdominal distension with vomiting for 5 days. The child was first born, full term, and delivered by cesarean section. After birth, the baby had a normal bowel movement, but at about 1 month after birth, she began to have abdominal distension, accompanied by poor appetite, mental fatigue, no apparent fever or vomiting, and the abdominal distension worsened progressively. After 2 days of symptomatic treatment in the local hospital with fasting and rehydration, the baby had diarrhea, and the abdominal distension was relieved by the discharge of dark green, pasty, foul-smelling stools. Similar symptoms occurred once in about 2 weeks and were relieved by conservative treatment. About 5 days ago, the symptoms of abdominal distension appeared again, gradually worsened and was accompanied by vomiting and fever, and the child had intermittent discharge of foul-smelling loose stools in small quantities each time. She was admitted to the hospital for diagnosis and treatment. Admission examination: mild dehydration anemia appearance, mental depression; abdominal distension, the whole abdomen can be seen intestinal type, no obvious pressure pain, rebound pain and muscle tension is not obvious; anal shape is normal, anus finger-pointing did not touch stenosis ring, rectal potbelly for viscous dark gray stool. Blood tests: WBC 8.6G/L, HGB 90g/L, PLT 180G/L; biochemical tests: AST 58U/L, ALT 40U/L, TP 46g/L, ALB 35g/L; abdominal X-ray showed a large amount of pneumoperitoneum. Admission diagnosis: incomplete intestinal obstruction (cause to be investigated). After admission, the child was given water fasting, nutritional support, warm saline reflux enema, and gentamicin 40,000 U retention enema after daily cleansing.3 days later, the child’s exhaust increased, the odor of stool decreased, and the abdominal distension was gradually relieved. Barium enema examination of the anal tube can only be placed into about 10cm, injection of dilute barium about 30ml, it is difficult to continue, was changed to pantethine glucosamine oral gastrointestinal imaging, 2 hours after the colon to about the lower part of the lower part of the descending colon, and again through the anal tube injection of barium imaging to see the distal colon has a beak-like narrowing of the thinning, and the proximal has been developed with the distal descending colon nearly connected to the colon, the diagnosis of colonic stenosis. After adequate preoperative preparation, surgical exploration was performed, during which the proximal colon was dilated with a diameter of about 5 cm, and there was an obvious stenotic section of the sigmoid colon with a length of about 4 cm and a diameter of only about 1.0 cm, with localized intestinal edema, and a diameter of about 3 cm in the distal colon and rectum, and the diagnosis was determined, and the stenotic section of the intestinal canal and the distal colon were confirmed to have ganglionic cell development by frozen pathology to exclude the congenital megacolon, and then the stenotic section of the colon was resected. After the diagnosis was confirmed and the ganglion cell development was confirmed by cryopathologic examination of the stenotic section of the colon and the distal colon to exclude congenital megacolon, a resection of the stenotic section of the colon was performed with the stenotic section of the colon as the central intestinal resection and enterostomy. Postoperative pathological findings: chronic inflammation of the colonic mucosa and a small number of dysplastic ganglion cells could be seen in the intermuscular area of the narrowed section of the intestinal canal.