Craniosynostosis is a partial loss of the skull and loss of the original complete shape of the head, caused by congenital developmental abnormalities or acquired sudden factors, mostly due to cerebral hemorrhage and surgical decompression of cranial hypertension or surgical resection of cranial lesions. The disease may manifest as headache, dizziness, loss of muscle strength, etc. Patients with cranial defects should be prepared to undergo surgery, and the success of the surgery can be better ensured by choosing good repair materials and doctors. Polyetheretherketone is a clinically appropriate choice for repair material. Patients who have undergone peek material cranial bone repair are no different from normal people. This is due to the histocompatibility of polyether ether ketone and the human body have a very good integration. Patients basically do not have rejection reactions. It is also more comfortable and thicker. It is similar to the human skull. Especially for pediatric patients, it can better adapt to the growth and development of human autogenous cranial bone. And it will have a lower infection and rejection rate. Importantly, patients do not have to worry about how the surgery will affect their appearance, as the repair with polyetheretherketone allows for precise extraction of three-dimensional data to create a personalized repair material that matches the structure of the patient’s bone window. What are the benefits of the surgery for the patient: The hard skull repair material can effectively prevent the brain from being impacted by external forces. Cranial bone repair also helps to improve problems such as impaired blood supply to the brain and abnormal cerebrospinal fluid circulation. The longer the cranial defect, the higher the incidence of cranial defect syndrome and secondary brain damage. Moreover, craniosynostosis also leads to a change in the shape of the cranial defect area, and the scalp is affected by atmospheric pressure, which makes it invaginate and compress the brain tissue. Therefore, in order to restore the confinement of the cranial cavity, maintain the physiological intracranial pressure stability and alleviate the cranial defect syndrome. After cranial defect, the skull should be repaired as soon as possible to avoid the above symptoms, which threaten the health of patients. Therefore, cranial repair should be performed as soon as possible. Cranial repair procedure: 1. First, a 3D CT scan of the patient’s skull is required to extract accurate 3D data for 3D reconstruction and 3D printing to produce a personalized PEEK repair material that perfectly matches the structure of the bone window. 2, The scalp is incised during the surgery, and the layers of tissue are carefully separated to expose the bone window, then the material is precisely affixed to the bone window and adjusted and reset. 3, well fixed with special lap screws, suture all layers of skin, and the surgery is complete. 4.After the operation, pay attention to give antibiotics to prevent infection, hemostasis and neurotrophic drug treatment; pay attention to observe the change of the patient’s surgical cavity drainage, change the medicine regularly and observe the incision healing. That is to say, after choosing the appropriate repair material for skull repair, there is no difference with normal people after the surgery recovery. Not only can’t be seen from the appearance, but also the pressure-bearing capacity of the skull is comparable to normal people, so patients don’t need to worry about the possible danger caused by the defect.