For esophagogastric fundic varices, about 90% of the causes come from liver lesions, such as already advanced cirrhosis. Especially in the decompensated stage of cirrhosis, esophageal varices are more obvious and often result in rupture of esophageal varices as well as hemorrhage, which may also cause upper gastrointestinal hemorrhage and vomiting of blood. Then there is hepatocellular carcinoma, as the blockage of veins by cancer emboli of hepatocellular carcinoma also causes esophageal varices, so the most serious lesion of esophageal varices comes from the liver, causing obstruction of venous return to the liver and establishing the collateral circulation of liver and body circulation. If esophagogastric varices are found, the first thing that should be considered is to check for liver lesions, such as cirrhosis and liver cancer.