Folic acid and progesterone can be taken together and must be taken together in the first trimester of pregnancy, especially for pregnant women who have a premonition of miscarriage. Because the main purpose of taking folic acid in the first trimester is to promote the development of the fetus’s nervous system, and the main purpose of taking progesterone is to protect the fetus. These two drugs must be taken together to ensure that the child is smart and to prevent miscarriage. When you take these two drugs, you can take them at a slight interval, for example, if you take folic acid at eight o’clock in the morning, you can use progesterone at ten o’clock, and then take them at an interval of two hours or so, so that the two drugs don’t have any interaction with each other. After using progesterone for a period of time, you must pay attention to go to the hospital for follow-up, blood test progesterone is not elevated, ultrasound has no heart tube pulsation, after three months you can stop folic acid.