The occurrence of generalized edema by infusion may be caused by too much infusion, and it may also be caused by metabolic disorders in the body, such as kidney failure, which leads to water retention in the body. Therefore, in case of generalized edema: First, the infusion must be stopped as much as possible, and if the condition requires infusion, the amount of infusion should be reduced as much as possible. Secondly, diuretics can be applied, commonly used are furosemide, anisodone or mannitol for dehydration and diuretic treatment. Third, must be regular blood retest electrolytes four, to understand the body’s potassium ions, sodium ions and chloride ions, general dehydration will easily lead to the above ion loss, if the loss is serious, must be intravenous replenishment. Fourth, if it is caused by kidney failure, must deal with the problem of kidney function, the conditions can apply for hemodialysis method of treatment.