Down’s syndrome screening is more appropriate between 12-16 weeks of pregnancy. By taking the pregnant woman’s blood serum, the fetal development can be analyzed and evaluated based on the pregnancy week, age, height and weight, which can determine whether the fetus has congenital genetic problems. If the risk of Down’s syndrome is determined to be moderate or high, do not be overly nervous and have further non-invasive DNA testing. Because Down’s syndrome screening is only 65% accurate, amniocentesis or non-invasive DNA testing can accurately determine whether the fetus has a congenital genetic problem. If there are no problems with these two tests, the baby can be born without any problems.