Slight tingling sensation in the chest and esophagus may be caused by reflux esophagitis, or it may be caused by tuberculosis, coronary heart disease and other diseases. 1. Reflux esophagitis: Suffering from reflux esophagitis will cause a mild tingling sensation in the chest and esophagus, and the patient will also experience acid reflux, heartburn and other adverse symptoms, and there may be a painful sensation when swallowing food, and some patients will have a sense of a foreign body in the throat, which will cause difficulty in swallowing. 2. Tuberculosis: patients will cough up sputum, cough, hemoptysis and other symptoms, may be accompanied by weakness, low-grade fever, night sweats and other systemic symptoms, with the development of the disease pain will worsen. 3. Coronary heart disease: patients usually experience chest tightness, panic, chest tightness and other discomforts, which may also cause arrhythmia, and dizziness or shock at the onset. Chest esophagus often have a slight tingling sensation can also be seen in other diseases, it is recommended that patients seek medical attention in a timely manner, so as to avoid delaying the condition.