Pain in the lower abdomen caused by stones is usually caused by irritation of the urinary tract mucosa by stones and can be treated with antispasmodic and analgesic drugs. Patients should first of all take bed rest and reduce their activities, which will make the pain less painful. In addition, commonly used antispasmodic drugs, mainly tamsulosin as well as nifedipine and other drugs for analgesia. Different drugs can be used depending on the nature of the pain. For mild pain, non-steroidal anti-inflammatory analgesic drugs, such as ibuprofen and aspirin, can be used. For moderate to severe pain, you can use drugs with better analgesic effect, mainly opioid analgesics, such as tramadol, dulcolax, etc. Generally, oral antispasmodic and analgesic drugs are effective for most of the pain caused by stones. To completely cure the pain, the stones can be removed surgically.