The cause of hand and foot convulsions is due to various causes of lower blood calcium, low blood magnesium, hypernatremia and increased muscle nerve excitability in the body, mainly manifested by violent flexion of the wrist and ankle joints, muscle spasms, which can be accompanied by laryngospasm and convulsions. Vitamin D deficiency causes rickets in children, osteochondrosis in adults, and hypoparathyroidism caused by various reasons, as well as hypernatremia, hypomagnesemia, and alkalosis caused by many reasons in the body can cause hand and foot twitching. Hand-foot twitching is a clinical manifestation, and after it is found, we need to find the cause, and also need to distinguish it from other causes of hand-foot twitching, such as high fever, convulsions, epilepsy, and convulsions caused by hypoglycemia. When hand and foot convulsions occur, we should actively control the convulsions and laryngeal spasms, because untimely treatment may cause life-threatening, and at the same time, we should supplement calcium, using intravenous or oral calcium supplements, and also actively treat the primary disease, such as vitamin D deficiency or hypoparathyroidism.