(1) Isolated brain metastasis with resectable pulmonary lesion and non-small cell lung cancer, the brain lesion can be surgically resected or treated with stereotactic radiation therapy, while the primary lesion in the chest will be treated according to the principle of staging. (2) Isolated adrenal metastasis and lung lesion is resectable non-small cell lung cancer, the adrenal lesion can be considered for surgical resection, and the primary lesion in the chest is treated according to the principle of staging. ③ Isolated nodules in the contralateral lung or other lobes of the ipsilateral lung can be treated according to the respective staging of the two primary tumors.