Hand, foot and mouth disease is transmitted in many ways, mainly through human contact to spread, specifically divided into the following: 1, the virus of hand, foot and mouth disease through saliva, herpes fluid, feces, etc.; 2, also through the virus-carrying hands, towels, cups, toys, tableware and various supplies; 3, underwear has had indirect contact, can also spread the virus of hand, foot and mouth disease; 4, carrying the virus of the patient’s Saliva and secretions of patients carrying the virus, also carrying the virus, can be transmitted to others in the form of droplets; 5, contact with water sources contaminated by the virus can also be transmitted; 6, the disinfection of instruments in the hospital is not in place, resulting in cross-infection, is also one of the ways of transmission of hand, foot and mouth disease.