HFMD is most contagious within a week from the onset of symptoms. During this time, HFMD can be transmitted by various means, such as the rash on the hands, which contains many HFMD pathogens, and the herpes fluid, which can be transmitted by direct hand contact or by contaminating other indirect objects that come into contact with other children. In addition, the pathogen of HFMD can also be present in the respiratory tract and spread through respiratory droplets, for example, two children talking together without masks are likely to transmit to others. Therefore, HFMD is more contagious during this week and is more likely to spread through these two ways.