Proglumide is mainly used for the treatment of peptic ulcer, gastritis and duodenal bulbaritis. Side effects can lead to allergic reactions such as skin rashes, and adverse reactions in various systems such as insomnia and dry mouth. 1. Effectiveness of Proglumide Due to the anti-gastrin effect of proglumide, it can inhibit gastric acid and pepsin, and reduce the irritation of the above substances on the mucosa of the stomach and duodenum. Thus, it protects the gastric mucosa and other effects, so it can be used for the treatment of peptic ulcers such as gastric ulcers, duodenal ulcers and other peptic ulcers, as well as for the treatment of gastritis and duodenal bulbar inflammation and so on. 2. Side effects of Proglumide The side effects of this drug are mainly allergic reactions such as skin rashes and itching, and the drug should be stopped immediately in case of an allergic reaction. Neurological symptoms, such as insomnia, may also occur with this drug. Liver damage may also occur, usually as a mild elevation of aminotransferases. Gastrointestinal reactions such as dry mouth, constipation, and bloating may also occur. Even temporary leukopenia is seen in the blood system. Side effects such as soreness in the lower extremities may also occur. It is contraindicated in patients with complete obstruction of the cystic duct and bile duct. In conclusion, the use of Proglumide needs to be under the guidance of a medical professional.