Occupational poisoning is not caused by contact with productive dust, it is poisoning caused by contact with industrial poisons and absorption of industrial poisons by workers in the course of their labor. Occupational poisoning includes lead poisoning, mercury poisoning, etc., but also includes irritant gas poisoning, asphyxiating gas poisoning, etc. Occupational poisoning due to the toxicity of poisons and the role of characteristics, exposure to different doses, poisoning performance is also different. When many kinds of poisons act on the body at the same time, they will involve all systems of the whole body, and the damage of many organs will appear. If the same poison is a different type of poisoning, the damage to the human body involves different organs. Occupational poisoning is generally divided into acute occupational poisoning and chronic occupational poisoning. The treatment of occupational poisoning can be divided into symptomatic treatment, etiologic treatment and supportive therapy. Symptomatic treatment is mainly to alleviate the symptoms caused by the poison and promote the recovery of body functions. Etiologic treatment is to reduce or eliminate the disease-causing substances and to deal with the disease-causing mechanism of the poison. Supportive therapy can improve the patient’s physical condition and promote the recovery of the patient’s organism.