Elevated creatinine due to hypertension is usually irreversible. A long history of hypertension or poorly controlled blood pressure can cause increased intraglomerular pressure and renal arteriosclerosis, which leads to a decrease in blood supply to the kidneys and a decrease in glomerular filtration and excretion. When the glomerular filtration function decreases to 1/3 of the normal level, blood creatinine starts to rise, and then the glomerular function cannot be reversed. Therefore, creatinine elevation caused by hypertension is usually irreversible. The progression of kidney disease can be slowed down if patients actively control their blood pressure with medication. For patients with elevated creatinine due to hypertension, it is recommended that they go to regular hospitals in time and receive standardized treatment under the guidance of doctors.