Prevention of coronary artery blockage mainly take antiplatelet drugs such as aspirin, lipid regulating drugs such as atorvastatin calcium tablets and so on. 1. Antiplatelet drugs: play a role in anti-platelet aggregation, reduce thrombosis, to avoid further narrowing of coronary artery vessels. Clinically used drugs are aspirin, clopidogrel and so on. Taking this kind of drugs need to observe whether there is bleeding gums, black stool, blood stool. 2. Lipid-regulating drugs: can lower triglycerides and cholesterol, but also can stabilize atherosclerotic plaque, prevent plaque shedding, to avoid stenosis, blockage of blood vessels. Commonly used drugs in the clinic are atorvastatin calcium tablets, resuvastatin calcium tablets. Taking the drug needs to monitor the liver function situation. Normally, it is necessary to pay attention to low-salt and low-fat diet, and eat more fresh vegetables and fruits. The above drugs should be used under the guidance of a physician, and should not be used blindly to avoid adverse effects.