Lung involvement is seen in 85% of patients with mixed connective tissue disease. Of these, only 27% present with clinical symptoms, mainly shortness of breath, chest pain and dry cough. Interstitial fibrosis, pleural effusion, pleural hypertrophy or pulmonary hypertension occur in a minority of patients. Patients with lung involvement should eat soft, easily digestible foods, such as celery, and drink the juice to help clear toxins and waste from the gallbladder and large intestine, as well as provide essential fatty acids to the body. Patients with lung involvement should go to a regular hospital for examination. Lung involvement is associated with pulmonary hemorrhage in 12% to 29% of patients with spinal vascular disease and is an important factor in morbidity and mortality. Hemoptysis is a common manifestation of pulmonary involvement, ranging from blood in the sputum in mild cases to massive hemoptysis in severe cases. Most cases present within 1 month of admission, but can also be chronic, with dyspnea and anemia, and pulmonary hemorrhage can lead to severe hypoxemia. Common imaging features are alveolar shadows without pulmonary edema or infection. An elevated carbon monoxide conversion factor (≥30%) is also indicative of pulmonary hemorrhage, and the diagnosis can be confirmed by bronchoalveolar lavage. Some patients with small-vessel pulmonary vasculitis have clinical imaging features consistent with an interstitial course resembling idiopathic pulmonary fibrosis. Pulmonary involvement may present with cough, dyspnea, chest tightness, etc. Prompt medical attention is required to detect these symptoms. Lung tissue is rich in connective tissue and blood vessels and is more susceptible to involvement, and the chance of lung involvement increases as the disease progresses. Once the disease progresses to pulmonary fibrosis, the lesions are irreversible and can seriously affect the quality of life of the patient in later stages. People with extra-articular damage, such as acute iritis and lung involvement, also need to be treated with adrenal glucocorticoids. Long-term use of glucocorticosteroids can do more harm than good, so they should not be used routinely, especially not in large or medium doses for a long time. They are only suitable for those who are allergic to NSAIDs or whose symptoms cannot be controlled by NSAIDs, and even if they are applied, small doses are generally appropriate, such as prednisone (prednisone) not exceeding 10 mg daily. Only when the symptoms are severe and cannot be controlled by NSAIDs or small doses of hormones, larger doses are available. When the symptoms are controlled and the slow-acting drugs have worked, the dose should be gradually reduced until it is discontinued. For individual peripheral joints that are resistant to NSAID therapy or have a single episode, intra-articular injections of rimethasone, Depo-Provera, and tretinoin acetate may be used.