Acute leukemia m5 is called acute monocytic leukemia, which belongs to the acute myeloid leukemia. Primitive monocytes and naïve monocytes ≥ 30% and monocytes ≥ 80% in the bone marrow are the diagnostic criteria for acute leukemia. The causes of leukemia are complex and include the following: 1, working in chemicals, fertilizers, leather, etc. Such people are often exposed to chemicals such as benzene, which can easily cause leukemia; 2, if there are leukemia patients in the family, there is the possibility of heredity; 3, long-term exposure to radioactive substances, such as X-rays, R-rays, etc.; 4, viral infections. The clinical manifestations of acute monocytic leukemia are the same as those of other leukemias, i.e., they show bleeding, fever, enlarged lymph nodes, liver and spleen. The more unique manifestations are frequent gum enlargement and swelling, blue-gray macules on the skin, and central nervous system leukemia more commonly. This type of leukemia is potentially curable, and with aggressive chemotherapy, suitability in mating for hematopoietic stem cell transplantation, and active and effective postoperative prevention and treatment, the disease has the potential for complete recovery.