There is no fastest way to stop coughing at night, and it needs to be treated according to allergy, respiratory system, circulatory system, digestive system, etc., such as anti-allergy, anti-infective, cardiac, acid suppression, etc. 1. Allergy, such as allergy to mites, etc., can use loratadine and other antihistamine treatment, the development of cough variant asthma, but also need to use albuterol and other bronchodilators. 2. Respiratory system, such as pneumonia, bronchial asthma, etc., can also cause nocturnal cough, and need to be treated with antibiotics such as ceftazidime, or bronchodilators such as salbutamol and formoterol. 3. Circulatory system, such as heart failure, can also cause nocturnal coughing, generally need to control the amount of in and out, combined with diuretic such as torasemide, cardiotonic such as digitalis and other drugs. 4. Digestive system, common gastroesophageal reflux can also stimulate the esophagus to cause night coughing, can use lansoprazole and other acid-suppressing treatment. The cause of the cough needs to be clarified after medical examination, and the medication should be used according to the doctor’s prescription.