Human albumin is a human blood product, and since the raw material comes from human blood, although the raw plasma is screened for relevant pathogens and measures to remove and inactivate viruses are incorporated into the production, there is still a theoretical potential risk of transmitting certain pathogens, and the pros and cons should be weighed when used clinically. Human albumin is relatively rare and is only used as a vascular osmolarity modulating agent and does not have a prophylactic effect against disease. The main side effects are: chills, fever, facial flushing, rash, nausea, vomiting, etc. Occasionally, rapid infusion may cause vascular overload leading to pulmonary edema, and occasionally allergic reactions. It is contraindicated in severe allergy to albumin, hypertension, acute heart disease, heart failure, severe anemia, and renal insufficiency. The use of human albumin should be noted as follows: (1) those who are obviously dehydrated should be rehydrated at the same time; (2) over-injection can cause dehydration, increased circulatory load, congestive heart failure and pulmonary edema; (3) freezing should be strictly prohibited during transportation and storage; (4) it should be used with caution in pregnant women or women who may be pregnant, and if necessary, it should be used under the guidance and close observation of a physician.