There is no fixed amount of rehydration fluid for infectious shock, it should be based on the actual situation of the patient (e.g. kilogram of body weight, loss of body fluids, etc.), and the principle of rehydration fluid is to start with crystalloid and then colloid, and to start with fast and then slow. Infectious shock refers to the shock caused by gram-negative bacteria and other pathogenic bacteria infection, for the diagnosis of patients should be immediately fluid resuscitation. The principle of fluid resuscitation in infectious shock is crystalloid followed by colloid, fast then slow, and no less than 30 ml/kg of crystalloid should be given in the first 3 hours of treatment. In the first half hour, 20 ml/kg of crystalloid should be replenished, and after the rehydration volume is about 40~60 ml/kg, central venous pressure should be measured while blood pressure, respiration, heart rate and other indexes should be closely monitored. Continue to input 1/2 or 2/3 tensor solution at a rate of 5~10ml/kg/h for the next 6~8 hours. The infusion should be maintained for 24 hours after correction of shock by continuing to enter 1/3 sheet solution at a rate of 2~4ml/kg/h. Infectious shock is an acute and serious condition that requires prompt and correct treatment to ensure life safety.