Diagnostic criteria for infective shock generally include symptoms, foci of infection, laboratory tests, etc. The principle of treatment generally includes anti-shock and anti-infection. 1. Diagnostic criteria: diagnosis of infectious shock usually has obvious foci of infection, such as skin infection, biliary tract infection, etc.; the existence of systemic inflammatory response, blood routine often shows elevated leukocytes, neutrophils, C-reactive protein; there is a drop in blood pressure, diastolic blood pressure is less than 40mmHg can be considered the patient is in a state of shock, the skin is often wet and cold. Urine output is reduced, and when normal, the typical urine output is about 0.5mL/kg per minute. Another manifestation is an elevated level of lactic acid, and if lactic acid is greater than 1.2mmol/L, it is considered to be organ perfusion insufficiency. Blood culture test will culture the pathogenic bacteria. 2. Treatment principle: mainly for anti-shock, anti-infection, usually give rapid rehydration, replenish blood volume, correct acid-base intoxication, and at the same time, give early, adequate amount, broad-spectrum, empirical antibiotic anti-infection treatment. Infectious shock is one of the more serious clinical diseases, once appeared need to be treated in time.