Total cholesterol is the sum of cholesterol contained in all lipoproteins, and the normal range for adults is 2.86 to 5.98 mmol/L (110 to 230 mg/L), and if patients whose liver function is checked find cholesterol in this range, then total cholesterol is elevated. High total cholesterol levels, physiological causes and 2 pathological causes. 1. Physiological causes Unscientific diet can cause high total cholesterol. If a large amount of food containing high total cholesterol like animal offal is consumed, it will cause too much cholesterol in the body and eventually cause high total cholesterol, so this is the cause of high total cholesterol and it is related to our daily diet, which should be noticed. 2. Pathological causes (1) Obstructive jaundice This is caused by obstruction of bile drainage, the appearance of lipoprotein-X in the blood and hypercholesterol synthesis in the liver, mainly due to an increase in free cholesterol. It causes high total cholesterol, so obstructive jaundice is one of the causes of high total cholesterol. (2) Hepatocellular damage Esterification of cholesterol in the blood, in the blood of patients with cirrhosis, severe hepatitis and other severe damage, and reduced blood cholesterol. In this liver disease patients, it is recommended to use German anti-hepatitis B hyperoxia negative therapy for the treatment of elevated total cholesterol has good efficacy, generally, patients receiving 1 to 2 courses of treatment will be able to return to the original level and safe, non-toxic side effects. Hazards of total cholesterol 1. Fatty liver, liver tumor, bile duct obstruction, bile duct stone, pancreatic head cancer, etc. cause bile discharge disorder and increase the ability of liver to synthesize cholesterol, and increase the concentration of total cholesterol in blood, mainly free cholesterol. In cases caused by biliary tract tumors, cholesterol levels are often higher than in cases of common bile duct stones. The absolute cholesterol ester level is also reduced in cases with coexisting hepatocellular damage. 2. Hyperlipidemia Primary hypercholesterolemia, such as familial hypercholesterolemia, type I~V hyperlipidemia, sporadic hypercholesterolemia, etc. 3, other diseases such as acute blood loss, multiple myeloma, senile cataracts, etc. may also appear elevated TC. Also seen in Vonl Gierke disease, Weber Christian disease, LCAT deficiency, psoriasis, and mucinous edema, yellow tumor disease, etc.