You can take anti-inflammatory drugs for tooth pain, such as cephalosporin, amoxicillin, erythromycin, azithromycin, metronidazole tablets, periodontin, etc. If the pain is particularly severe, you can take ibuprofen-type painkillers, and if the toothache is also accompanied by fever, you can take antipyretic drugs when necessary. Tooth pain mainly has the following causes: pulpitis, periapicalitis, gingivitis, periodontitis, tooth fracture, wisdom tooth pericoronitis and other diseases of different dental and periodontal tissues, in addition to the use of drug treatment, but also need to go to professional medical institutions for treatment, suffering from pulpitis and periapicalitis should do root canal treatment, in order to completely and thoroughly solve the pain; gingivitis and periodontitis cause swelling and discomfort of the whole mouth teeth. The treatment needs to be done by ultrasonic scaling or periodontal scaling; wisdom tooth peri-coronitis needs to be extracted after the acute phase of inflammation to prevent recurring pain.