Gastrointestinal colic is seen in diseases such as gastritis, gastric ulcer, gastrointestinal cramps, and enteritis. Anticholinergic drugs, drugs to inhibit gastric acid, antibiotics and so on can be used. 1. Anticholinergic drugs: Gastrointestinal colic is caused by spasm of gastrointestinal smooth muscle, so anticholinergic drugs can be used, such as scopolamine. Adverse reactions include dry mouth, blurred vision, and increased heart rate. Glaucoma and prostate hypertrophy are prohibited. 2. Drugs to inhibit gastric acid: gastrointestinal colic may be caused by gastric ulcer, enteritis, in order to treat the cause can be used to inhibit gastric acid and protect the gastric mucosa drugs, such as omeprazole, magnesium aluminum carbonate chewable tablets. Adverse reactions include diarrhea, constipation and so on. 3. Antibiotics: Gastritis is often caused by Helicobacter pylori infection, which can be treated with quadruple therapy, such as omeprazole + clarithromycin + amoxicillin + bismuth potassium citrate, and enterocolitis usually requires anti-infective treatments such as norfloxacin and levofloxacin. If persistent gastrointestinal colic occurs, go to the hospital in time for treatment and use reasonable and standardized medication under the guidance of the doctor.