Women with particularly itchy vaginal opening need to consider the following possibilities: First, gynecological inflammation. Patients with mycotic vaginitis infection, trichomonas vaginitis infection and bacterial vaginitis infection are very prone to significant vulvar itching. These three diseases can lead to an abnormal increase in leucorrhea, and the stimulation of secretions can cause itching of the vagina and vulva. Second, if there are skin lesions of the vulva, vulvodynia can also cause itching. If a woman is allergic to sanitary products or underwear, or if she eats allergic food, it may also cause itching at the vaginal opening. For itching at the vaginal opening, gynecological examination is needed. Most of the patients can have their symptoms relieved after active and symptomatic treatment.