Pain in the ankle can be gout, but it can also be caused by rheumatoid arthritis, trauma and other causes. 1. Gout: Gout may indeed present with symptoms of ankle pain, along with redness and swelling at the ankle, and the presence of irregularly sized growths at the ankle. Patients can be diagnosed by means of uric acid level measurement, joint fluid examination and x-ray examination. 2. Rheumatoid arthritis: rheumatoid arthritis is a kind of autoimmune disease mainly characterized by symmetric polyarticular swelling and pain, and the pain in the ankle and wrist may be related to rheumatoid arthritis, and the patient needs to improve the diagnosis by blood sedimentation, anti-cyclic citrullinated polypeptide antibody, and ultrasound of the musculoskeletal bone. 3. Trauma: If the patient has ankle pain, and there is a history of trauma before the pain, the ankle pain may be related to trauma. It is recommended that patients go to rheumatology and orthopedics departments in regular hospitals to get a clear diagnosis as soon as possible and actively cooperate with doctors to prevent the condition from developing and affecting the therapeutic effect.