High tPSA consider the possible existence of prostate tumors, tPSA is also known as total prostate-specific antigen, when there is a high tPSA need to carry out further examination, timely determination of the type of disease, and take targeted treatment. tPSA is prostate-specific antigen, mainly used to screen prostate tumors, more sensitive, the normal range is between 0-4 ng/ml, when tPSA is high, you need to carry out rectal fingerprinting, prostate ultrasound, prostate magnetic resonance and other tests to make a comprehensive judgment, if there is an abnormality, you should carry out further prostate puncture biopsy, as soon as possible to clarify the diagnosis and treatment. There are many interfering factors for high tPSA, such as rectal examination, catheterization, etc. If there is any abnormality of tPSA, it should be treated actively to avoid the serious consequences of delaying the condition.