The woman who experiences the pregnancy and the growth of her child is the happiest woman in the world. It is a wonderful feeling when you sense a little life growing in your belly, and at that moment, the nature of motherhood makes all women have only one wish: I want my baby to be healthy! But we all know that viral hepatitis is an important infectious disease that endangers the health of our people, of which hepatitis B has the highest infection rate and is the most harmful. It is estimated that there are about 90 million hepatitis B virus carriers in China, and there must be some mothers-to-be among them. These mothers-to-be wish to be happy women, and moreover desire their babies to be healthy for life. As a hepatitis B positive mother-to-be, there must be some problems bothering you, so see if I can help you? 1. Can a person with chronic hepatitis B virus (HBV) infection get pregnant? Before a woman with chronic HBV infection plans to become pregnant, it is best to have her liver function evaluated by a specialist in infection or hepatology. Infected women whose liver function is always normal can have a normal pregnancy; those with abnormal liver function can have a pregnancy if they return to normal after treatment and are rechecked normal for more than 6 months after stopping medication. Pregnancy during antiviral therapy must be done with caution. If pregnancy occurs during the use of any antiviral drugs, the mother-to-be must consult a specialist at the hospital to assess the various risks of the drugs used in order to decide whether to interrupt the pregnancy or to continue antiviral treatment. 2. Must liver function be reviewed regularly after pregnancy in patients with chronic HBV infection? Yes! Liver function must be reviewed regularly after pregnancy in patients with chronic HBV infection, especially in the early and late stages of pregnancy. For those who have normal liver function in the first test, if there are no clinical symptoms of hepatitis, they should be rechecked once in 1-2 months; if the alanine transferase (ALT) is elevated, they should ask the relevant professional physician to consult and determine the interval of rechecking and rechecking items according to the specific value of ALT combined with the bilirubin level. 3.Can the application of hepatitis B immunoglobulin (HBIG) during late pregnancy prevent mother-to-child transmission of HBV? It is not recommended! In the past, for mothers-to-be who are positive for hepatitis B, it was advocated to inject HBIG in late pregnancy to neutralize the virus in the body and prevent intrauterine infection of the fetus. Therefore, the application of HBIG is now not recommended for HBV-infected pregnant women in late pregnancy. if a hepatitis B positive mother-to-be personally wishes to be injected, she should consult a specialist at a medical institution to assess the risk of side effects. 4.Can a cesarean delivery reduce the chance of mother-to-child transmission? Cesarean delivery cannot reduce the rate of mother-to-child transmission of HBV. It is believed that the contraction of the uterus during natural childbirth “squeezes” the placenta, prompting the virus in the mother to enter the fetus, causing intrauterine infection, cesarean delivery theoretically shortens the time of delivery, the baby will come out of contact with the mother’s blood for a shorter period of time, the risk should be low, so theoretically cesarean delivery can reduce the mother-to-poppy transmission of HBV. However, clinical observations have found that although cesarean delivery is short, the same exposure to blood will occur. Natural delivery, although the newborn will come into contact with the mother’s blood, but the newborn generally has very intact skin has a barrier effect on the virus. Recent studies also prove that the newborns of pregnant women chronically infected with HBV have no significant difference in the rate of HBV infection between cesarean delivery and natural delivery of newborns after regular blocking measures are taken, indicating that cesarean delivery does not reduce mother-to-child transmission of HBV. 5.If the mother is hepatitis B positive, what vaccinations should the baby receive within how long after birth? Vaccination against hepatitis B is the most effective measure to prevent HBV infection, and the positive conversion rate of anti-HBs is as high as 95%~100% after the whole vaccination of newborns. When a pregnant woman is positive for HBsAg, regardless of whether the HBeAg is positive or negative, the newborn must be given HBIG and full vaccination against hepatitis B (3-dose regimen at 0, 1 and 6 months) in a timely manner. HBIG needs to be administered within 12h after birth (theoretically the earlier the better). After taking the above formal preventive measures, the protection rate for newborns of HBsAg-positive but HBeAg-negative pregnant women is 98%-100%, and for newborns of both HBsAg and HBeAg-positive pregnant women is 85%-95%. If HBIG is not used and only vaccine prevention is applied, the overall protection rate is only 55%-85%. If the baby is born prematurely or with other diseases after birth, you should follow the medical advice to implement blocking measures. 6.Can a mother who is positive for hepatitis B breastfeed her baby? HBsAg and HBV-DNA can be detected in breast milk, and some scholars believe that cracked nipples, excessive sucking or even biting of nipples by infants may transmit the virus to infants, but these are theoretical analyses, but there is a lack of evidence-based medical evidence. However, just in case, breastfeeding is not recommended, but it is a pity not to breastfeed because of this. However, we need to pay attention to the following: the mother should wash her hands and wipe her nipples before breastfeeding; it is best to isolate the child and the mother’s supplies; if the nipples are severely cracked or the baby has ulcers in the mouth, breastfeeding can be properly suspended, and during the suspension of breastfeeding, milk must be expressed to maintain lactation; regular testing of the baby’s serological markers of hepatitis B; regular testing of the mother’s liver function. 7.When the mother is HBsAg negative, but the father is HBsAg positive, do I need to inject the baby with HBIG? Injection is recommended! Although semen cannot cause HBV infection in the fetus, close contact with the father, usually due to his care of the newborn, increases the risk of infection in the baby, therefore, it is better for the baby to be injected with HBIG. similarly, other family members who are HBsAg positive, if they are in close contact with the baby, it is better for the baby to be injected with HBIG. if the father or other HBsAg positive family members are not in close contact with the baby, the baby For the record, mother-to-child transmission is the main cause of chronic HBV infection in China. If the mother-to-be is HBsAg-positive, her baby is at high risk of HBV infection. Globulin (HBIG). This is really important! The treatment and prevention of any disease is a serious topic. If you are a hepatitis B positive mother-to-be, you must remember to consult a specialist before, during and after pregnancy regarding treatment and prevention, and not to blindly use medication based on your own fragmented knowledge, nor to be too careless and miss the best time for treatment.