Pus in the inguinal region is considered to be secondary to a local soft tissue infection, and can also be formed after suppuration of the inguinal lymph nodes, mostly secondary to immunocompromised patients. In addition, some patients can be secondary to soft tissue infections of the lower extremities, such as alone or cellulitis, and are also prone to lymph node, that is, reactive hyperplasia of lymph nodes in the inguinal region, or even abscess formation, and the patient has significant fever. Surgical treatment with incision and drainage is an option, and postoperative symptomatic anti-infective treatment and regular drug changes are also required. In some patients, the infection is secondary to the sebaceous cyst, which is also prone to infection because of the special anatomical location of the inguinal region. Therefore, for early diagnosis of sebaceous cyst, surgical excision should also be chosen in a timely manner during the limited stage to avoid aggravation of the condition and unnecessary pain to the patient.