The pathologic changes of follicular papillary thyroid cancer are papillary cancerous tissue with follicular growth. The diagnosis of follicular papillary thyroid cancer is considered if the thyroid cancer tissue is microscopically found to be papillary with papillary branching formation accompanied by follicular growth of cancerous tissue. Generally, papillary carcinoma and follicular carcinoma belong to two pathological types of thyroid cancer, accounting for more than 90% of thyroid cancers. Follicular carcinoma is a malignant tumor of the thyroid gland that differentiates into follicles; papillary carcinoma has several histologic subtypes, including follicular type. Pathologic changes include multiple papillary branches with calcified vesicles in the interstitium of the vessels within the branches and clear, hairy-glass nuclei. Follicular papillary carcinoma of the thyroid has been diagnosed and should be treated aggressively as prescribed by the doctor.