Rejection reactions occur mainly due to poor preoperative sterilization and inadequate postoperative care, and can have serious consequences once they occur and can increase the rate of infection. As a rule, if the patient has more oozing from the incision and no significant pain in the first 2 weeks after surgery, it can be considered a rejection reaction. Once a rejection reaction is diagnosed, the implanted nasal prosthesis should be surgically removed immediately. For early acute rejection reaction, the prosthesis can be removed through the original incision, blood and exudate can be removed, and the latent cavity can be flushed with a small amount of antibiotics and dexamethasone solution, and the wound can be sutured and treated with anti-inflammatory therapy after surgery. For patients with chronic reactions, the skin has broken down to form an infection, the ulcer is large, and the prosthesis has been exposed at the ulcer, the prosthesis can be removed via the ulcer. For patients with small ulcerated areas, another concealed incision should be considered to facilitate the treatment and healing of the ulcerated skin.