STDs refer to diseases transmitted mainly through sexual contact and are a collective term for a group of diseases (6 in total), so there is no characteristic clinical manifestation and transmission through sexual contact is their common denominator. STDs include syphilis, AIDS, condyloma acuminatum, genital herpes, genital mycoplasma trachomatis, and gonorrhea. Among them, syphilis, AIDS, and mycoplasma can be without any symptoms or symptoms are not characteristic and can be considered as having no typical clinical symptoms and require laboratory tests to confirm the diagnosis. Genital herpes is a cluster of small blisters in the above mentioned areas, similar to perioral herpes simplex, and is often associated with pain. Gonorrhea is diagnosed by a purulent discharge from the urethra or perineum, which can be confirmed by medical history and examination. STD is not a disease, because the pathogen and pathogenesis are different, the performance is also different, and some of the disease can be without any clinical symptoms, laboratory tests are the only criteria to confirm the diagnosis. It is important to be clean, have a healthy sexual attitude, have protected sex, and seek medical attention and monitoring when there is a risk of infection.