Condyloma acuminatum is a common sexually transmitted disease caused by human papillomavirus (HPV) infection, which is mainly manifested as a proliferative lesion of the skin and mucous membrane. It is a common clinical disease caused by human papillomavirus (HPV) infection, mainly manifested as skin mucous membrane proliferation lesions. A, the prevalence of condyloma acuminata and risk factors. 1, research shows that the more sexual partners in a lifetime, the higher the frequency of sexual intercourse and the younger the age of first intercourse, will lead to an increase in the incidence and recurrence of condyloma acuminata. 2, long-term birth control pills will increase the risk of HPV infection. 3, combined or previous history of chlamydia, gonorrhea, genital herpes or trichomoniasis infection will increase the probability of HPV infection. 4, AIDS patients, organ transplant recipients, etc. have an increased risk of developing condyloma acuminata during immunosuppression, and can be generalized. The second, HPV infection characteristics and virus immune escape mechanism. HPV latent infection refers to the state of HPV presence that does not cause any clinical manifestations and histological changes after HPV enters the skin and mucous membranes, and can only be detected by molecular biological methods. Subclinical infection refers to HPV infection, but warts have not yet appeared, and lesions can only be detected with the aid of magnification, colposcopy, urethroscopy or external application of 3%-5% glacial acetic acid. The potential foci of HPV infection and subclinical HPV infection are detected in the urethra of male patients with condyloma acuminata. The virus can be infected through the foreskin and secretions to the foreskin and coronal sulcus, etc. In women with vulvar warts, there may be latent HPV foci and subclinical HPV foci in the cervix, and the genital area may be infected through menstruation and leukorrhea. The lack of specific diagnostic methods and targeted treatment measures for HPV subclinical and latent infections has resulted in incomplete treatment of HPV infected areas, leading to recurrence of condyloma acuminata. The actual fact is that the actual person’s own factors lead to the recurrence of condyloma acuminata. 1, the body immune. The actual fact is that you can find a lot of people who are not able to get a lot of money from the internet. 2, psychological factors. Most patients with condyloma acuminata show a strong sense of fear and guilt, condyloma acuminata recurrence often makes patients depressed, anxious and other psychological disorders. The patient’s bad mood can affect the body’s immune function, leading to increased viral replication, recurrence of condyloma acuminata patients often over-clean, destroy the local skin mucous membrane barrier, resulting in condyloma acuminata easy recurrence. 3, bad lifestyle habits. Research shows that smoking and alcohol abuse can reduce the body’s immunity, is one of the risk factors leading to the recurrence of condyloma acuminata. Other factors; during pregnancy the body’s cellular immune function is physiologically suppressed, can lead to the development of the disease, the increase in the volume of warts, making treatment more difficult, the recurrence rate is higher. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things.